The Arabidopsis circadian clock incorporates a cADPR-based feedback loop
Dodd A. and Gardner M. and Hotta C. and Hubbard K. and Dalchau N. and Love J. and Assie J. and Robertson F. and Jakobsen M. and Goncalves J. and Sanders D. and Webb A.
Science, 2007
Accepted
Abstract
Transcriptional feedback loops are a feature of circadian clocks in both animals and plants. We show that the plant circadian clock also incorporates the cytosolic signalling molecule cyclic adenosine diphosphate ribose (cADPR). cADPR modulates the transcriptional feedback loops of the circadian oscillator and drives circadian oscillations of Ca2+ release. The effects of antagonists of cADPR signalling, manipulation of cADPR synthesis, and mathematical simulation of the interaction of cADPR with the circadian clock indicate that cADPR forms a feedback loop within the plant circadian clock.
BibTex Entry
- @Article{,
- author = {Dodd A. and Gardner M. and Hotta C. and Hubbard K. and Dalchau N. and Love J. and Assie J. and Robertson F. and Jakobsen M. and Goncalves J. and Sanders D. and Webb A.},
- journal = {Science},
- title = {The Arabidopsis circadian clock incorporates a cADPR-based feedback loop},
- year = {2007},
- note = {Accepted}
- }
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